What is Botox?
The toxin (neurotoxin) of the bacteria called Clostridium Botulinum, which causes food poisoning, prevents the release of acetylcholine in the muscles and acts by causing partial paralysis.
Areas of use of Botox in urology
1-Urinary incontinence, interstitial cystitis and bladder pain syndrome
The most current and most common medical treatment in urology does not yield results or As an alternative to medication, it has also been used successfully in urinary incontinence, overactive bladder, neurogenic bladder, interstitial cystitis and bladder pain syndrome. Before deciding to apply it, it should be ensured that there is no bladder cancer. Botox material is diluted and injected systematically into the bladder muscle at 20-30 separate points, using an endoscope (cystoscope) under local or general anesthesia, at a dose of 100 to 300 units in total. The procedure takes an average of 15 minutes, and if there is no bleeding, there is no need for a urinary catheter.
2-Botox application in Prostate Enlargement
It is seen as an effective and reliable method in patients who have urination difficulties due to prostate enlargement, as an alternative to drug treatment or in patients who do not benefit sufficiently from drugs, and in some selected patients who are not suitable for surgery. This method is not a standard and routine method used in the treatment of prostate enlargement. The procedure involves the injection of 100-300 Units of Botox material, depending on the size of the prostate, under local or general anesthesia, rectal, transurethral (through the urinary tract through the cystoscope) or perineal (the area between the testicle and anal) ultrasonography guidance, with a needle of appropriate length, especially into several areas close to the outside of the prostate.
As a result, the material given has the same effect as the drugs called alpha-blockers given to patients due to prostate complaints. The procedure has some side effects, including; Allergic reactions include painful urination, urinary obstruction, urinary tract infection. In case of hypersensitivity to Botox, also called Freys syndrome, it should be used more carefully and in lower doses. The toxic dose range in humans is 2500-3000 Units, this dose should not be exceeded.
Situations in which Botox should not be used
-
Pregnancy and breastfeeding,
-
Those who use certain medications that affect the muscles rda (aminoglycoside, penicillamines, calcium channel blockers, magnesium, cyclosporine)
-
Patients with muscle diseases (ALS, Myasthenia gravis, Eaton-Lambert Syndrome)
-
Patients with bleeding disorders (Hemophilia etc.)
-
Patients with allergy to Botox
Read: 0
