It is very difficult to monitor the clinical course of Epstein-Barr (EBV), which is defined as an unusual virus today. This virus causes many diseases. There is a serious scientific inadequacy in defining the different clinical pictures caused by the EBV virus.
The disease progresses differently in individuals infected with the EBV virus;
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. Active infection develops (kissing disease) ,
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. It may progress as an asymptomatic infection,
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. Chronic infection may occur.
When faced with the EBV virus, the virus is not eliminated from the body, but remains in the body as a 'latent virus' for life. When the immune system is weakened, this virus is reactivated and EBV virus-related diseases develop.
Kissing disease caused by EBV is seen in adolescents and adults in developed countries.
EBV infection is a disease of infancy and early childhood in our country.
The rate of being infected with Epstein-Barr virus increases with age.
It is seen that 95% of the adult population is infected with EBV. Most of the time, individuals do not realize that they have this infection.
Epstein-Barr causes clinical pictures by affecting lifelong.
Long-term effects can be examined under two headings,
Cancer formation
Autoimmune diseases
EBV virus enters the circulation by infecting B lymphocytes. In individuals with a normal immune system, the virus remains for life without causing any problems some cancers
In cases where immune system functions are impaired, the EBV virus causes many 'autoimmune' diseases as a result of the 'autoimmune' reaction.
Epstein-Barr virus has carcinogenic potential,
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.Burkitt Lymphoma
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.Nasopharyngeal Cancer
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.Hodgkin's Disease
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.Post-transplant developing lymphoproliferative disease (PTLD)
they are clinical pictures caused by the EBV virus. It has been reported that it may be a factor in the formation of some cancers other than the cancer types mentioned above.
EBV virus, which is defined as oncogenic virus, is defined as the main cause in some cancers and it is possible in some cancer types. Attention is drawn to the fact that there may be a relationship.
There is insufficient information on the EBV virus that causes cancer.
The answer to the questions 'In which conditions and in what way does this virus, which progresses as a kissing disease or asymptomatic infection, have a carcinogenic effect?' is not known.
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It is emphasized that nutritional deficiency, which impairs the immune system, especially in children, is a factor in secondary infections, as well as stress factor in adults.
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EBV virus causes many autoimmune diseases;
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.Multiple Sclerosis (MS)
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.Rheumatid arthritis,
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.Lupus,
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.Sjögren's syndrome,
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.Celiac,
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.Type 1 diabetes is known to be associated with the EBV virus.
It has been proven that EBV has a role in 'Multiple Sclerosis' as a result of long-term studies. pass this infection The development of MS increases 32 times in individuals with rheumatoid arthritis compared to the normal population.
We are at the point where the EBV virus and autoimmune disease are innumerable.
about autoimmune diseases caused by EBV virus There are many diseases that I could not bring to the agenda regarding both EBV cancer and EBV autoimmune patients.
In conclusion ;
It was brought to the agenda in a short time that EBV is a latent virus, it causes serious symptoms, infection in early childhood can increase the risk of cancer, and EBV vaccine is on the agenda in a short time. I would like to state that protection from this virus is very important.
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