AMH is short for Anti-Mullerian Hormone. AMH is secreted by the granulosa cells of the ovaries in women. AMH is a hormone that regulates the amount of reproductive follicles in the ovary and the rate at which they grow and are consumed. AMH level remains at 2-5 ng/ml during the fertility period and after menopause, it decreases to unmeasurable values.
The superiority of AMH over FSH and LH, which are other hormones used for this purpose to date, is It is secreted directly by female ovarian cells. Therefore, it has the advantage of being able to directly show the activity and quantity of ovarian cells. FSH and LH are secreted not from the ovary, but from another organ called the pituitary, and their effects on the ovary are indirect. Therefore, they can be affected by many other conditions and may give misleading results.
In addition to determining the ovarian reserve and activity in women, AMH can also be used to investigate granulosa cell cancers of the ovary.
AMH is also important in pediatric age research. In fact, AMH is the most important hormone that determines the transition of children to puberty and also the hormonal development of men and women. Therefore, it is used both in the study of early or late puberty and in the distinction between gender disorders and bisexuality.
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