Vitamin D is a group of sterols, which are among the fat-soluble vitamins that regulate the metabolism of calcium and phosphorus minerals, and which, unlike other vitamins, are hormone and hormone precursors produced in the body. (Organic substance in alcohol structure)
Dvit consists of 2 forms. D2; Ergocalciferol from plants. D3; After exposure of 7 dehydrocholesterol, which is taken from animal foods and also found in the skin of the individual, to sunlight, Vit.D3 (cholecalciferol)
People meet a large part of their Dvit requirement by making them in the body through sunlight.
Liver, fish, egg yolk, salmon, mackerel, milk, broccoli, green onions are foods rich in Dvit.
When Dvit is taken in diet, it turns into active forms in liver and kidney. In this process, parathormone (secreted from the parathyroid gland), calcium and phosphorus levels are also effective. It is seen in those who are alive, obese, elderly, those who give birth frequently, and those with nutritional deficiency. It affects many organs, including immune (immune system) cells, endothelium and myocardium (heart muscle).
At the same time, it is stated that the active form of Vit.D (1,25(OH)2D) exerts an antihypertensive (blood pressure lowering) effect by suppressing renin (hormone that causes narrowing of the vessels) levels from the kidneys.
Vit D – OBESITY RELATIONSHIP
Vit.D deficiency and obesity, which is the cause of the other is still controversial. Vit.D deficiency suppresses fat breakdown (lipolysis) by increasing the passage of Calcium (ca+2) from the outside into the cell, and stimulates lipogenesis (fat production). With the same mechanism, it causes fat accumulation by suppressing the release of protein that enables the use of fats in the cell.
The increase in fat cells (adipocytes) and high blood lipids with vitamin D deficiency suggest that Vit.D deficiency is a cause of obesity.
The presence of Dvit deficiency together with obesity It is thought to be due to the spread of excess fat to the adipose tissue after being synthesized in the skin. This causes Vit.D to appear insufficient in the blood.
VIT.D EXCESSION
It results from taking supplemental Vit.D rather than through food.
Serum It causes toxicity by causing an increase in calcium level.
– Calcinosis; Accumulation of calcium in many organs.
– Hypercalcemia: (Increased blood calcium level) Heart rhythm disorders, mental status changes, vomiting, weight loss…
RELATED WITH VIT.D AND CANCER
Studies have reported that 20% of all cancer cases are caused by obesity and one of the mechanisms underlying this relationship is Vit.D deficiency.
It is necessary to measure Vit.D once in a while. But do not get support without having your blood Vit.D level checked. If you are taking it, have your blood level checked in between.
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