Pleasure drinks containing ethanol are called "Alcoholic Drinks". The history of alcohol is almost as old as human history. It started to produce alcohol with the sedentary life of humanity. The first brewing began about 8,000 years ago, when the Mesopotamians first bred barley to make bread. It is known that the Sumerians consumed beer and wine in the Godin Hills (Western Iran and Anatolia) 6 thousand years ago.
Alcohol-related liver injuries come up with a definition that covers a wide spectrum of diseases, from simple fatty liver to alcoholic hepatitis or cirrhosis, under the name of 'alcoholic liver disease'. It is the most common cause of cirrhosis in the European population. The intensity of alcohol consumption, especially in our region, has led to the processing of the issue from the perspective of the liver. You should know that you are not consuming an innocent product, and you should know that the amount of alcohol consumed has an important place in the risk of getting sick.
The acute syndrome of alcoholic hepatitis is severe and leads to poor outcomes. Although most long-term heavy drinkers will develop fatty liver, 10-35% will develop alcoholic hepatitis and 8-20% cirrhosis. Most alcoholic hepatitis occur in male patients, although women are more prone to alcohol-related liver disease. To prevent the development of cirrhosis, the lower limit of daily ethanol intake is 30-50 grams. Those who develop alcoholic hepatitis often consume more than 100 grams of alcohol per day. If daily ethanol consumption exceeds 40-80 grams in men and 20-40 grams in women, alcoholic liver disease will almost certainly develop within 10-12 years.
The combination of multiple environmental and genetic factors in alcoholic liver disease affects individual susceptibility. Alcohol intake history, physical examination and laboratory results are important steps in diagnosis. Fever, low blood pressure and tachycardia are important in patients with malnutrition. Jaundice and abdominal distension (ascites) are common, and most patients have altered consciousness. The liver is large and sensitive. The AST/ALT ratio of liver tests is usually above 2. GGT is significantly elevated.
Treatment in alcoholic liver disease consists of three categories: alcoholism treatment, nutritional support, and specific drug treatments. Professional psychiatry or substance abuse specialists must be included in the issue of alcohol cessation. Malnutrition criteria is a factor that increases negativity in patients with alcoholic hepatitis. It is important to give B vitamins (especially thiamine), folic acid and vitamin K. Most patients have a zinc deficiency. Vitamin and mineral support is continued for approximately 6 months to 1 year. Prednisolone, pentoxifylline, propylthiouracil, antioxidants and colchicine can be given to appropriate patients. A high-calorie diet is important.
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