It has been discovered that the blood of the mother and the baby mixes during pregnancy, resulting in free DNA fragments belonging to both. It has been understood that the DNA fragments that do not belong to the mother are an indicator of the genetic structure of the baby.
As a result of the examination of a small amount of blood sample taken from the mother's arm, information will be obtained about the possibility of the most common chromosomal disorders in the baby. In this test, which can be performed as early as the 10th week of pregnancy, the results are obtained in an average of 1 week.
Diagnosis of Down Syndrome from Maternal Blood occurs with twin and/or assisted reproductive techniques (IVF, etc.). It can be used safely in all pregnancies. This has been proven by many studies on this subject and published in serious scientific journals. You do not have to be a risky expectant mother (you need to be older, etc.) to be diagnosed with Down Syndrome from Maternal Blood. Scientific studies show that the majority of Down syndrome occurs in children born to mothers who are considered not at risk. For this reason, scientific studies have been conducted on "Down Syndrome Diagnosis from Maternal Blood" and it has been determined that this test can be used safely in pregnant women who are not at risk.
It is a non-invasive test as no invasive procedure is applied to the mother and therefore it is not included in classical prenatal diagnosis methods. Pregnancy with (CVS, amniocentesis, cordocentesis) does not carry any risk of miscarriage or infection. When these methods are taken together, it has been determined that approximately 1 in every 100 pregnancies ends in miscarriage.
As with all screening tests, although it is very low in the diagnosis of Down Syndrome from the mother's blood, a result can be obtained indicating that the baby has a high risk of the disease, even if the baby is not sick. The probability of obtaining this type of result (false positivity) in the diagnosis of Down Syndrome from Maternal Blood is the lowest compared to all available non-invasive tests; and when such a result is obtained, after your doctor's advice and consultation with your geneticist at the center that performs the test, your baby will be delivered by a method such as amniocentesis. It may be recommended to definitively determine whether your baby is sick or not.
Since "Down Syndrome Diagnosis from Mother's Blood" is a screening test, results showing the possibility of your baby being sick will be obtained and numerically By calculating the risk, it will be stated that the risk is low/high with a probability ratio specific to your pregnancy. A result of “yes” or “no” is contrary to the nature of all medical screening tests and is extremely wrong, both medically, legally and ethically. As a result of the diagnosis of Down Syndrome from the mother's blood, a "chromosomal problem risk of less than 1:10000" is a positive test result, and a "risk greater than 99%" is a negative test result.
Read: 0
