As the years pass, the production of proteins such as Collagen and Elastin, which provide the skin's elasticity and vitality, naturally decreases. Due to this decrease in production, wrinkles, sagging, skin discoloration and dulling occur on the skin. We call these symptoms “aged skin”. In a sense, old age is the process in which the healthy, fresh and vibrant appearance of our skin gradually diminishes and disappears after the age of 20. According to many serious academic studies, aging or old age is now seen as a "preventable disease". The first and most important feature sought in the technique to be preferred to erase or prevent the signs of aging is the applications that promise improvement and benefit, as well as permanence, with minimal harm to the patient. Rejuvenation with cell (Fibroblast) culture is the name of one of these methods. It has been used for aesthetic purposes since 2002. It is an application that has received FDA approval. For years, we have tried to deal with these problems of aging symptoms only by using temporary methods or under anesthesia, at great risk. Today, with the help of developing technology and new methods and techniques developed by tissue engineers, permanent and effective solutions have begun to be found for the aging problem in our skin (especially our face). The cell (fibroblast) culture transplantation method, which replaces the tissue loss in the skin, so to speak, the skeletal system and whose effectiveness continues even after 4-5 years, has started to be used increasingly in clinics in recent years. This method, which stops the signs of aging that time reflects on our faces and even rewinds time, is a cell therapy obtained from the person himself. In other words, the cells obtained from you will be used for you again. While the cells used in PRP, another similar method used in rejuvenation obtained from the patient's own blood, are blood cells (platelets), the cells used in this technique are fibroblasts obtained from the skin instead of blood.
What is rejuvenation with fibroblast cell culture?
What is rejuvenation with fibroblast cell culture? p>
The only way is to multiply the "Fibroblast" cells obtained from a lentil-sized biopsy taken from the patient in an improved safe laboratory environment and apply these new cells to the patient in 3 sessions for treatment purposes.
What is the function of fibroblast cells in skin renewal?
Fibroblasts are the basic cells of the connective tissue that give volume and durability to our skin. They are responsible for the production of collagen, which is the main substance of connective tissue and ensures wound healing. These cells are responsible for the production of elastic fibers and hyaluronic acid, as well as collagen protein. Fibroblasts are cells that produce fibrils in tissue. These cells are responsible for the elasticity and vitality of the skin.
How is it applied?
Tissue biopsy containing fibroblast cells is taken under local anesthesia from behind the ear or rarely from the inner surface of the forearm, which is the area that receives the least sunlight in our body. The area behind the ear is the more preferred area, as there will be no scars in the procedure area and because it is a hairless area.
The area where the biopsy is taken is easily closed using tissue adhesive or a single stitch. The biopsy taken is sent to laboratories selected for this purpose in appropriate environments and conditions. The cell multiplication process is completed under laboratory conditions and in 4 weeks.
The multiplied cells are applied in 3 sessions, 4-6 weeks apart. During each application, 20-40 million fibroblast cells are administered to the patient via an insulin injector to the desired area. When the procedure is completed, approximately 100-120 million fibroblast cells will be given to the patient.
Where and for which problems is it used?
For the removal and treatment of wrinkles and deep grooves (Face, neck, décolletage, back of the hands rejuvenation and filler), In facial renewal treatment with mesotherapy, In filling and erasing obvious sunken surgery scars, In correction of minimal complications regarding the remaining tissue and contour after the surgical procedure of the face, In rejuvenation and clarification of the genital area, In the treatment of non-healing wounds. It is used to close diabetic foot wounds, to support healing in burn treatment, to fill and erase scars that have left depths or pits such as acne and chickenpox, to stop the lifelessness of hair in hair loss and to trigger new hair growth.
Pregnant women. Since no studies have been conducted on it, it is not applied to pregnant women. However, it can be used in cancer patients under treatment.
When is the effect seen?
The effect and treatment begins to be seen as fullness and brightness on the skin a few weeks after the first application. However, the full results continue to increase and multiply months after the end of treatment.
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