Intratumoral Therapy in Early Diagnosis and Treatment of Lung Cancer

Lung cancer is the leading cause of cancer deaths in men and women (29%, 1.3 million people each year). The relationship between this disease and smoking has been definitively proven by research conducted since 1964. Today, smoking is the cause of 80-90% of lung cancer. Smoking is a lethal factor that threatens public health, so efforts are being made to protect public health and reduce the lung cancer risk of young people and passive smokers with very strict laws and precautions.

Unfortunately, lung cancer is often not diagnosed at an early stage, so the disease is very bad. It progresses and becomes very difficult to control. Due to the delay in early diagnosis of cancer, only 15% of cases that have spread to advanced stages can survive for 5 years. 75% of the patients are diagnosed with grades III or IV. It can be diagnosed at an early stage.

Symptoms of lung cancer: In the beginning, they are very ordinary or non-existent. Since ordinary complaints are ignored, the time to treat lung cancer is delayed. Below, some ordinary symptoms need to be taken into consideration

Early diagnosis of lung cancer is lifesaving in the treatment of the disease. In order to recognize and treat cancer at an early stage; cancer screening clinical strategy: High Risk group; male and female, over 50 years of age, smokers or those who have quit (risk of cancer is 87% in those who smoke 20 pak/year), passive smokers (risk of cancer is 20-30%).

  • Low density lung tomography (normal lung radiography should never be requested for screening)
  • Respiratory Function Tests
  • Bronchoscopy; bronchial lavage cytology)
  • These techniques to be performed in high-risk group people help in the early diagnosis of lung cancer and in recognizing the complaints caused by cancer before they appear

    Intratumoral chemotherapy, an intravenous or administration of more than one cytotoxic drug (cancer cell killer) through a catheterized needle through a flexible bronchoscope It is a new interventional bronchoscopy method that consists of injecting directly into the tumor tissue. Intratumoral chemotherapy, on the one hand, eliminates the tumor mass in the bronchus (airway) that causes obstruction; On the other hand, it has a specific cytotoxic (lethal) effect only on cancer cells without harming normal cells. The advantage of local delivery of therapeutic substances by intratumoral local injection is the equal distribution of the drug within the tumor tissue and the provision of a high local concentration that can never be achieved by intravenous route; On the other hand, no significant systemic side effects occur.

    BENEFITS OF INTRA TUMORAL LOCAL CHEMOTHERAPY:

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