Heart Disease in the Family

I HAVE A HEART IN MY FAMILY

When heart disease is mentioned in the family, coronary artery disease should come to mind.

• There must be a definite diagnosis of coronary artery disease in the family. Must have a history of heart attack, balloon, stent and bypass. In addition, sudden unexplained deaths at early and late ages should also be evaluated in this section.

• By the way, the family is first-degree relatives. Mother, father and siblings are evaluated.

• If one of the siblings has cardiovascular disease, the risk of cardiovascular disease increases by 30-40% in the other sibling.

• If twins The risk is 3 times higher than non-twin siblings.

• The risk is high if the mother and father have had a Cardiovascular Disease under the age of 50.

• If there is "sudden death" under the age of 50, the risk is higher.

• If the concept of family is expanded, if uncles, aunts and grandparents are included, this risk is 44% higher than for those who do not.

• Unfortunately, in some families, heart attacks and losses are more common at an early age.

• If there is Diabetes (especially insulin-dependent) and familial high cholesterol in the family, these additional factors may cause occlusion in the arteries. . control of these additional factors becomes more important. It should at least be evaluated and investigated as it may cause vascular occlusion.

• A gene study was conducted in 2018 involving 480 000 adults (1). In this study, around 1.5 million genetic variations were detected and analyzed. A new gene risk score was developed based on this data (metaGRS). 22,242 CAD persons with coronary artery disease were compared with 460.387 persons without coronary artery disease registered in the database. Accordingly, among the genetic variations detected, the chance of developing coronary artery disease was found to be 4.17 times higher in the top 20% group compared to the bottom 20% group.

• This means that : If you have coronary artery disease in your first degree relatives in your family, you definitely have heart disease. It doesn't mean you will be. If you only have certain genetic variations then the risk is high. Such genetic variations have been determined and can be used in the future to identify those who are in the really risky category.

• So having a family history of heart disease does not necessarily mean you will have heart disease.

• There are two important accompanying exceptions to this. . As I said above, insulin-dependent diabetes mellitus and familial high cholesterol are additional risk factors.

• In some families, sudden deaths at an early age are high without being linked to cholesterol or sugar. The number of people who reach 60 years of age in these families is very small. mostly men. this group may be the high risk genetic variation group we are talking about.

• The cases who had acute coronary syndrome (heart attack) in 2018 were examined (2). Heart attack was detected in 4.17% of 28,188 patients who were admitted to the hospital with chest pain. Family history was found in 31.4% of them. There are two important points in this study. heart attack outcomes were worse in those with a family history. secondly, coronary artery disease occurred both earlier and at younger ages in patients with a family history.

• Roughly, we can say that having a family history increases the risk of coronary artery disease by 30-40%.

• If the above-mentioned events have happened in your family, it is useful to be cautious. Have frequent and regular check-ups. Avoid excessive exercise and emotional turmoil. We see that emotional conflicts and turmoil are often effective, especially in those who have a crisis for the first time.

• BEFORE MEASURE AFTER CONSENT.

• Stay HEALTHY.

_{Read: 0}