Migraine - Botox Treatment

Botox Treatment in Chronic Migraine


Migraine form that shows the characteristic features of migraine pain and lasts more than 14 days per month

It is called chronic migraine. It is a condition that is not always easy to treat and disrupts the quality of life. There is pain that prevents the person from daily life for more than half of the month. When the drugs used in migraine prophylaxis fail, the treatment that has come to the fore in recent years is Botox.


Efficacy of Botox application in chronic migraine

Botox was first approved by the FDA in 2002 for the removal of facial wrinkles.

It is widely used in the cosmetic field. In medicine, Botox is used in the treatment of chronic migraine

as well as spasticity, excessive sweating, dystonia, hemifacial spasm, bruxism (teeth clenching).


The PREEMPT study* conducted in the USA evaluated the safety profile and effectiveness of Botox as a prophylactic (preventive) headache treatment in chronic migraine patients. The study revealed that the Botox treatment method is an effective solution in reducing the frequency and severity of pain in chronic migraine. Scientific studies have shown that this application is effective in three quarters of patients with chronic migraine. Based on this scientific evidence, the use of Botox injections for treatment of chronic migraine patients was approved in the USA and England in 2010, and in Turkey in 2011.

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How is Botox applied in the treatment of chronic migraine ?

In the treatment of chronic migraine, botulinium toxin is applied to 31 areas in 7 regions on the head and neck. p>

It is administered at a certain dose at the injection point and can be repeated every 12 weeks.

31 injections are administered through very fine needle tips. It is not a painful procedure that the patient cannot tolerate

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When does Botox treatment give results? How successful can it be?


According to clinical studies, botox treatment in chronic migraine begins to show its effect within 10 days after application. In a small percentage of patients There may be no benefit in the first application. In these patients, the effect begins after the second application at the 12th week.

Should Botox treatment be repeated?


After the first Botox application in the treatment of chronic migraine Even if the pain is completely relieved, the second dose is routinely administered 12 weeks after the first treatment. Studies have shown that attacks started again in a short time in patients who did not receive the second dose. The physician decides whether to administer the 3rd dose, which will be administered 12 weeks after the 2nd application, depending on the patient's current condition.

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