Investigation of Cognitive Flexibility and Resilience in Untreated Patients with Obsessive Compulsive Disorder

INTRODUCTION AND OBJECTIVE: Obsessive Compulsive Disorder (OCD) is a chronic disorder characterized by obsessions that may come in the form of intrusive thoughts, images, or impulses, as well as repetitive behaviors or mental acts, which can lead to severe disability if left untreated. In this study, it was aimed to examine the cognitive flexibility and psychological resilience in OCD and to compare them with healthy controls without OCD, and thus to contribute to the limited data in this area in the literature.

METHOD (Ethics Committee approval decision and number should be indicated):This The study was conducted by scanning the data of 25 OCD patients who met the admission criteria at the Health Sciences University Gülhane Training and Research Hospital psychiatry outpatient clinic, and 22 healthy individuals without a history of psychiatric disease who were matched in terms of age, gender and BMI. The data of the study were collected with a questionnaire consisting of 8 parts. The first part includes the data form on sociodemographic characteristics, the second part the Yale-Brown Obsession Compulsion Scale, the third part the Yale-Brown Symptom Checklist, the fourth part the Hamilton Anxiety Scale, the fifth part the Hamilton Depression Scale, the sixth part the Cognitive Scale. It includes the Resilience Scale, the seventh section Cognitive Flexibility and Control, and the eighth section the Adult Resilience Scale.

RESULTS: The study group consisted of 25 OCD patients (53.2%), 22 (46.8%) controls. It consists of 47 people in total. OCD patients ranged from 18 to 66, with a mean of 34.8 (12.5) years. The ages of the control group ranged from 20 to 42, with an average of 32.6 (6.0) years. There was no difference between the two groups in terms of mean age (z=0.192; p=0.847). 68% (n=17) of the patients in the study group were female, and 63.6% (n=14) of the control group were female. There was no difference between the two groups in terms of gender. There was no difference between the patients and control groups in the study group in terms of the scores they got from the cognitive flexibility scale and the resilience scale for adults (p>0.05 for each). The patient group had lower scores on the cognitive control and flexibility scale (p<0.05 for each). results are related to cognitive control and flexibility in the OCD group. Lower cognitive control and flexibility scores may affect the response of OCD to treatment. Large prospective studies are needed to better understand the mechanism of OCD in future studies.

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