- Inflammatory Breast Cancer
- Paget's Disease of the Breast
- Breast Cancer in Men
- Pregnancy and Breast Cancer
Inflammatory Breast Cancer
- It constitutes 1.5-3% of all breast cancers.
- Breast tissue is commonly red and tender, with shrinkage on the breast skin.
- Due to this appearance, it can be confused with a breast infection (mastitis) and is treated with antibiotics.
- A mass in the breast may be palpable, or it may be widespread without forming any mass.
- It is a type of breast cancer with a very rapid and poor clinical course.
- Tumor spread to the axillary lymph nodes is present in approximately 2/3 of patients at the time of diagnosis.
- TNM. It is considered as IIIB according to the staging system.
- Treatment is primarily systemic chemotherapy and, if appropriate, hormonotherapy. If there is a response to these treatments, surgical treatment (mastectomy) may be tried.
Paget's Disease of the Breast
- Breast It is a very rare type of breast cancer seen in the head.
- It starts in the milk ducts and spreads to the nipple and the darker colored part (areola) around it.
- Tenderness, itching, burning and intermittent blood in the nipple. Complaints such as nipple discharge may be observed.
- Skin crusting and discharge may occur. Because of this appearance, it can be confused with eczema.
- A biopsy is necessary for differential diagnosis.
- Approximately 1/3 - 1/4 of the patients have spread to the axillary lymph nodes at the time of diagnosis. However, since the diagnosis is often made at an early stage due to the complaints of the patients, the success of the treatment is also high.
- Since it is often necessary to remove the nipple, it is usually treated with mastectomy and reconstruction in suitable patients instead of breast-conserving surgery.
Breast Cancer in Men
- It constitutes less than 1% of all breast cancers.
- Its incidence is high in North American and British men, Jews and blacks.
- It is often seen in older men; It is most common between the ages of 60-69. Approximately one fifth of patients have blood Before ser is detected, there is gynecomastia (growth of male breasts similar to female breasts). It has also been claimed that some chromosomal anomalies develop as a result of estrogen therapy or radiotherapy and trauma in those with endogenous high estrogen levels.
- The picture of the disease is the same as in women.
- Breast mass, nipple shrinkage and They may have complaints of discharge, mass involvement of the skin, wounds and pain.
- They have similar survival times to women whose tumor is at the same stage, but since the majority of cases are at an advanced stage (stage III and IV) at the time of diagnosis, their survival rates are higher. is bad.
- The classical treatment method is modified radical mastectomy (removal of the entire breast and removal of the armpit lymph nodes related to the breast). Today, if there is no clinical involvement in the axillary lymph nodes, sentinel lymph node sampling is performed. If necessary, postoperative radiotherapy is performed and additional treatments such as chemotherapy and hormonotherapy are applied.
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