Smoking Increases the Frequency of Acute Myeloid Leukemia (AML)!

Smoking continues to be a public health problem all over the world and in our country. Every year, 6 million people around the world die from smoking-related causes. It is estimated that this number will reach 8 million in 2030.

More than 7000 substances harmful to health are released as a result of burning tobacco. 10 types of cancer (such as lung, kidney, bladder, cervix, esophagus, stomach, pancreatic cancer) and 18 other diseases (such as aortic enlargement, cataract, pneumonia, gingivitis) have been identified that are associated with smoking.

ACUTE LEUKEMIA AND SMOKING RELATIONSHIP

Leukemias that develop rapidly and appear suddenly are called "acute leukemias". The more common type of acute leukemia in adults is AML. For the last 10 years, it has been thought that one of the causes of myeloid leukemia is smoking. In a review published by Italian researchers in 2016 (1), it was stated that the frequency of AML was higher in adults who smoke than in never-smokers. Heavy and long-term smoking has been associated with an increased risk of leukemia. Interestingly, the risk of leukemia decreases significantly in individuals who have quit smoking for more than 20 years. Men were found to be more at risk than women, and this was attributed to men's smoking habits (intensive and long-term use). Although the relationship between smoking and leukemia is not fully understood, it has been shown that nicotine and some nicotine-related substances cause cancer in animal models. Chromosomal disorders occur due to benzene, formaldehyde or radioactive components (polonio 210) contained in cigarettes. In addition, changes in the immune system and the number of white blood cells in circulation are also blamed.

Attention should be drawn to the harms of smoking through preventive medicine practices. Only in this way will it be possible to reduce smoking-related diseases and their heavy economic burden. '' he stated.

 

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