Infertility
Those who cannot have children for 1 year despite having regular sexual intercourse on average twice a week are called infertile. One in every 10 couples faces this problem. If the sperm analysis is not suitable, it is also considered infertile.
In Vitro Fertilization
In Vitro Fertilization (IVF) is a form of treatment applied to women who cannot become pregnant by classical methods, and it is a form of treatment applied to women who receive sperm and sperm from the man. It is the placement of embryos, which are formed as a result of taking eggs from the woman and combining them under laboratory conditions, into the uterus. Fertilization under laboratory conditions is achieved either spontaneously (in vitro fertilization) or by placing a single sperm into a single egg (microinjection).
When is in vitro fertilization treatment? begins?
As a result of the test and examination, the treatment of couples who are planned to have in vitro fertilization begins in the 2nd-3rd month of menstruation.
Who can undergo IVF?
Tubal factor;Women with permanent damage to their tubes for any reason
>Male factor;Men with problems in sperm count, motility or structure
Cervical factor;Problems related to the cervix
Hormonal factor unexplained; Couples in whom pregnancy cannot be achieved even though no problems can be detected in both men and women
Microinjection:
A single sperm is injected under a special manipulator under a microscope under completely sterile conditions.
Reasons for microinjection
Those with very low sperm count
Ratio of normal shaped sperm % Those who have fewer than 4 sperm
Those who have not been fertilized in previous IVF attempts
Those who do not have any sperm but whose sperm is taken by testicular biopsy (in this case, the procedure is called TESA)
Ovulation induction (stimulation of the ovaries); Normally, a healthy woman produces only one egg each month. Our aim is to increase our chances of pregnancy by obtaining many eggs that are candidates for quality embryos and transferring more than one embryo.
There are different protocols for ovulation induction. The most commonly used birth control pill is between the 17th and 20th weeks. nasal spray or After the injection in the arm, examinations and treatment begin when the first menstrual bleeding occurs. The patient is closely monitored while using ovulation induction medications. Estradiol (E2), progesterone and LH hormones are checked in the blood and ultrasound monitoring is performed. Follow-up ends when the follicles reach 17 mm (at least 3) in approximately 8-10 days.
Afterwards, pregnyl or prophasis is performed for the eggs to hatch. Eggs are collected after 32–37 hours. Following embryo transfer within 2-5 days, pregnyl or prophasis can be continued at 3-day intervals for up to 20 days in patients deemed necessary.
After embryo transfer;
Daily activities can be done after 1 hour of bed rest
Sexual intercourse and vaginal douche are prohibited for 2 days
Progesterone supplementation is given when necessary.
In vitro fertilization risks;
Multiple pregnancy
Ectopic pregnancy
OHSS development due to overstimulation of the ovaries
Which patients cannot undergo in vitro fertilization?
Advanced age patients
Men who have no sperm in their semen or testicular biopsy.
Women who do not have a uterus for any reason.
Patients whose hormone test results are not suitable.
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