Gonarthrosis is a disease that is frequently seen in our society and causes our patients to apply to our clinic with knee pain, difficulty in walking and deformity.
Treatment of gonarthrosis is essentially divided into medical and surgical.
In medical treatment. Nonsteroidal anti-inflammatory, preparations containing glucosamine chondroitin sulphate, intra-articular hyaluronic acid and PRP (platelet reach plasma) applications are performed.
The purpose of this article is to inform our patients about stem cell application in gonarthrosis patients.
What is a Stem Cell?
Cells in our body that can constantly renew themselves and have the ability to differentiate are called "stem cells". Another feature of stem cells, which are the main cells found in the human body and can transform into all kinds of body cells, is that they create many new stem cells from a single cell. Stem cells in our body are mainly derived from the Umbilical Cord,
Amniotic membrane,
They are produced from Placenta,
Bone Marrow,
Adipose Tissue.
Stem Cell obtained from Fat Tissue;
Fat tissue (adipose) consists of the combination of fat cells. 10-15% of the total body weight of a healthy adult individual is fat tissue; It is a rich source of cells that can be used in the repair and regeneration of damaged tissues of the musculoskeletal system.
Adipose-derived stem cells; Vascular endothelial growth factor (VEGF), Hepatocyte growth factor (HGF), Insulin-like growth They secrete growth factors such as factor 1 (IGF-1). With this feature, it increases angiogenesis (vascular formation), ensures oxygen and nutrients are transported to the area where it is injected, and activates repair mechanisms.
Stem cell therapy; It is a treatment method that aims to reveal the body's own healing potential by injecting stem cells isolated from a part of the body (usually fat tissue or bone marrow) into the damaged area of the body.
Very There are various methods of obtaining stem cells. The most commonly used method is the stem cell method obtained from fat tissue, due to its benefits such as stem cell richness, affordability, and ease of preparation and application.
With this method, a small amount of fat tissue is Lipoaspirated. It is removed by liposuction method. By using a number of natural methods, a tissue rich in stem cells is obtained in a short time. This cell population rich in stem cells obtained; It is applied to the damaged area to repair tissues damaged for any reason and return them to their natural state.
Lipocell, which is injected into the damaged area of the body, separates the capillaries from the capillaries and turns into active mesenchymal stem cells (MSC) in response to the damage. It is a system that ensures the continuity of cells that are found in capillaries of origin and can turn into macrophages.
The application takes approximately 20 – 30 minutes and consists of 3 stages;
Filtration
Lipoaspiration
Washing, Separation, Obtaining purified adipose tissue
Are there any side effects in stem cell treatment?
There is no serious pain or damage reported in the area where the stem cells were injected. Only rarely, there may be a slight amount of pain in the application area. Has There are no restrictions on children continuing their normal activities.
In addition, the lipoaspiration area is max. It heals in 7-8 days.
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