It is a disease that causes curling in the fingers of unknown cause. It is more common in men and over the age of 50. It is usually seen in Caucasians and is more common in Northern Europe. It usually starts with a small nodule on the skin of the palm of the hand. Over time, these folds progress, become fixed, and the person cannot fully open his finger.
It is a disease of the solid structure in the palm called fascia. While this structure normally contains 95% type 1 collagen, in this disease it is replaced by type 3 collagen. This collagen causes the formation of a harder and thicker fascia.
The most affected finger is the ring finger, followed by the little finger and middle finger, but it can be seen in all fingers.
Although it is usually painless, some People may experience complaints such as mild pain and itching.
Although the exact causes have not been proven, some factors are blamed. These include alcohol, diabetes, smoking, other systemic diseases, genetic transmission, and working in a job that involves constant hand trauma.
The course of the disease varies from person to person. Treatment is initially with physical therapy. There are those who recommend cortisone injection. In later periods, treatment may be tried by dissolving the hardened tissue with surgery or clostridial collagenase enzyme. Treatment with this enzyme is an expensive method. Dupuytren's disease is a disease in which relapses and progressions can occur despite surgical treatment. Spontaneous regression and recovery of the disease does not occur.
This disease occurs more rapidly in patients with nodules on the upper part of the fingers, in those who are diagnosed at a young age, in those with a positive family history, in patients with lumps on the soles of the feet (Ledderhose disease) and in those with Peyronie's disease in the penis. and has a serious course.
Treatment: It can be performed with needle aponeurotomy, collagenase injection, segmental fasciectomy, fasciectomy with skin excision (dermofasciectomy) and skin graft (patch). Even amputation may be applied in severe disease.
During the treatment with fasciectomy, nerve injury, vascular injury, infection, hematoma, complex regional pain syndrome and skin healing problems may occur.
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