- Virus infections of the perineum
Human papillomavirus (HPV), is a non-enveloped, double-stranded virus belonging to the Papillomaviridae family. It is a strong>DNAvirus. More than 200 types of HPV are known, and more than 40 types are thought to be transmitted through sexual intercourse and infect the anogenital area. Other viruses seen in the perineum are herpes simplex virus and poxvirus (cause of Molluscum contagiosum).
Condyloma accuminatum: HPV is an anogenital infection of the vulva, vagina, Single/multiple, flat/fluffy, cauliflower/brain-shaped lesions may be seen in the perineal and perianal regions. The number and size of lesions are variable. Lesions appear on average 2.9 months after sexual intercourse. In most patients, the causative agent is type 6 and/or type 11.
Risk factors: Increase in the number of sexual partners, suppression of the immune system (steroid use, HIV infection, organ transplantation, etc.) and smoking cause an increase in the disease. It is thought that circumcision of the sexual partner reduces the prevalence of the disease.
Diagnosis: Diagnosis is made by cytological examination of the cervix and demonstration of HPV DNA.
Treatment: strong> Medical, cytodestructive and immune-mediated treatment methods, whose superiority over each other have not yet been demonstrated, are applied. Additionally, cryoablation, laser ablation, electrocautery and excisional methods can be tried.
Epidemiology: It is the most common disease transmitted through sexual intercourse. HPV is seen in 10-20% of the unvaccinated adult population, and its incidence has begun to decrease in vaccinated societies. In our country, the presence of HPV has been proven in 25% of women in their reproductive period. It has been shown that the rates of HPV DNA accompanying abnormal and normal cytology are 52% and 27%, respectively. It has also been reported that the rates of abnormal cervical cytology in our country are lower than in European and North American countries. This may be due to socio-cultural differences, lack/absence of population-based screening programs, or lowHPVprevala. It can be explained by nsi.
Cervix (cervical) cancers: The World Health Organization estimates that more than 2 million women in the world have cervical cancer and 1/3 of these women die. In short, a woman dies from cervical cancer every two minutes in the world.
Protection: Pap smear test should be performed regularly every year after the age of 25. Condoms do not provide complete protection against this disease.
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