Insulin is a hormone secreted from the pancreas and regulates our body's sugar metabolism. Insulin operates in the body by binding to a structure called the insulin receptor. If insensitivity develops in these receptors for various reasons, even though there is sufficient amount of insulin in the body, it cannot be detected by the tissues and cannot enter the cell and function. In this case, insulin resistance is mentioned. In other words, insulin resistance (ID) is the inability to exert its biological effects despite the presence of insulin in circulation. Metabolic disorder in the form of decreased insulin-mediated glucose utilization by tissues and increased glucose production by the liver forms the basis of insulin resistance. In such a case, the body is forced to secrete more insulin than normal, and excess insulin causes a feeling of hunger, appetite, and therefore weight gain, edema and fat in the body.
Why does insulin resistance occur?
Insulin resistance occurs due to genetic predisposition, sedentary lifestyle, hormonal disorders and unhealthy nutrition. The addition of a sedentary lifestyle to the increased consumption of processed foods today increases the risk of insulin resistance.
Which diseases accompany insulin resistance?
Insulin resistance adolescence and pregnancy. While it may develop physiologically/temporarily during periods, it may be accompanied by diabetes, hypertension, high cholesterol, metabolic syndrome, use of certain medications, polycystic ovary syndrome, liver and kidney diseases, infectious conditions and stress.
Insulin resistance. Can't he really lose weight?
Insulin resistance makes it difficult to lose weight. Those with insulin resistance feel hungry more and eat more frequently, feel late satiety, desire for sweets, irritability when hungry, trembling in the hands, cold sweats, weakness and fatigue quickly. In order to lose weight, in addition to reducing meals, it is necessary to choose foods that have a low glycemic index, low calorie content, high fiber content and make you feel full.
How is it diagnosed?
In evaluating the metabolic status associated with insulin resistance, fasting and postprandial blood sugar and HbA1c values should be measured. When necessary, a sugar loading test (oral glucose tolerance test) should also be performed. insulin Waist circumference of patients with n resistance and metabolic syndrome is important. In individuals with a waist circumference over 80cm in women and over 94cm in men, fasting blood sugar over 100 mg/dl, blood pressure over 130-85mm/hg, or use of antihypertensive medication with a diagnosis of hypertension, triglyceride level over 150mg/dl or HDL -If two of the criteria of cholesterol (good cholesterol) level being lower than 50mg/dl in women and 40mg/dl in men are present, an evaluation should be made by accepting the presence of insulin resistance.
Is there a treatment for insulin resistance?
The primary step in the treatment of insulin resistance is lifestyle changes. Medical nutrition therapy, increasing exercise and movement, and ensuring sleep patterns are important.
In the treatment of insulin resistance, first a blood test is performed and the resistance level is measured. In people with high resistance, the level can be returned to normal with 2-3 months or at most 6 months of treatments. When the insulin resistance level returns to normal, the obstacles to weight loss are eliminated. Therefore, patients quickly lose their appetite and lose weight. In addition, heart disease, susceptibility to cancer types and diabetes are prevented.
Treatment with some medications may be recommended for patients who cannot implement lifestyle changes or do not benefit from them. Metformin group drugs reduce the risk of developing diabetes by 30%, especially in patients with an HbA1c of 5.7-6.4%, fasting and/or postprandial blood sugar above the normal limit, a history of gestational diabetes, and a body mass index greater than 35.
People. Nutrition and exercise regulations should continue throughout life and weight gain should be prevented.
Read: 0
