What is Bullous Pemphigoid? Symptoms and Treatment

What is Bullous Pemphigoid? Symptoms and Treatment

Bullous pemphigoid is an important skin disease that causes non-deep wounds that crust over with the bursting and opening of fluid-filled blisters on the body surface over time. The disease does not have a different name used among the society. Bullous diseases are in the group of autoimmune diseases. Local or widespread bullous (fluid-filled bubble) lesions are seen accompanied by itching. In 20% of affected patients, bullae do not appear at all. Bullous pemphigoid disease, especially accompanied by bullae, adversely affects the quality of life of the person. Bullous pemphigoid disease can be seen in any age group, but it affects the elderly population more. The disease is rarely seen in children. The incidence of the disease does not differ according to gender, it is equally distributed in men and women.

What is Bullous Pemphigoid?

Bullous pemphigoid is the most common in the category of autoimmune skin diseases. Its incidence increases with advancing age and is more common in individuals over 60 years of age. The incidence of the disease is equal in men and women. However, there are studies in which women are affected more by the disease depending on racial characteristics, HLA genotypes and environmental factors. Although the disease is rare in children, it affects girls more frequently. If bullous pemphigoid is not treated, it can turn into a chronic disease that negatively affects the quality of life of the individual. Bullous pemphigoid disease is not contagious. The patient's wounds are not transmitted by contact, blood or other ways. Gestational pemphigoid (Pemphigoid Gestationes) is a special type of bullous pemphigoid disease seen during pregnancy. The disease occurs in the second or third trimester of pregnancy, sometimes after childbirth. The redness starts in the navel and abdomen and then spreads to the whole body. Bleeding after redness is followed by the formation of bullae. While the bullae heal, they do not leave a scar (scar), but spots on the skin and, rarely, small superficial keratin cysts (milia) occur.

What Causes Bullous Pemphigoid Disease?

The body's immune system mechanism's own skin Bullous pemphigoid disease occurs as a result of the severe reactions to the skin layer. As a result of these abnormal reactions, the autoa Although the cause of antibodies is not known exactly, some factors trigger the disease. treatment

  • Trauma
  • Burn
  • Some drugs
  • Diuretic drugs (diuretic) “furosemide”, some antibiotics “benzathine penicillin” ”, hypertension drug “captopril”, nonsteroidal anti-inflammatory agents (NSAIDs) (painkillers) are drugs thought to cause bullous pemphigoid disease. Since bullous pemphigoid is an autoimmune disease, other autoimmune diseases may accompany. Concomitant diseases are:

    What are the Symptoms of Bullous Pemphigoid Disease?

    The most common symptoms of bullous pemphigoid disease are itching and bulla formation. The inside of the bullae is usually filled with clear fluid, but can sometimes be hemorrhagic (bloody). The size and density of the lesions vary. Lesions remain in the body for long periods of time, such as weeks or months. The most common areas are surfaces such as armpits, groin, elbow bends. Physical symptoms vary according to the subgroups of bullous pemphigoid disease. Mucosal lesions occur in 10-30% of patients with classic bullous pemphigoid. While mucosal involvement mostly covers the oral (mouth) mucosa, the eye, nose, pharynx (pharynx), esophagus (esophagus) and genital mucosa are rarely affected. As in many autoimmune diseases, the evaluation of bullous pemphigoid pathology is the most important step in the diagnosis of the disease. Bullous pemphigoid used in the diagnosis of methods are:

    The findings of bullous pemphigoid in children show some differences. For example, the face, palms and soles of the feet are frequently affected in infants. Children older than one year are less affected in these regions. While genital involvement is rare in newborn babies, it is seen in approximately half of older children, especially girls. Involvement in girls can sometimes be limited to the genital area.

    How is the Treatment of Bullous Pemphigoid Disease?

    Bullous pemphigoid doctors are experienced dermatologists. In the presence of the patient's general condition, clinical picture and other accompanying diseases, dermatologists, family physicians, neurologists, geriatricians, geriatric nurses, psychologists and physiotherapists take part in patient treatment as a team. At the same time, family members also play an active role in the care of the patient. Due to the recurrent nature of the disease and its chronicity, important steps play a role in the follow-up and treatment. These important steps are as follows:

    Various treatment methods are used in bullous pemphigoid disease. These treatment methods are as follows:The practices that patients with a diagnosis of Bullous Pemphigoid should pay attention to in their daily lives are as follows:Bullous pemphigoid is an important chronic disease that negatively affects the quality of life and has serious complications. The disease can be brought under control by following the experts well and applying modern treatment methods. Health in the presence or suspicion of disease It is important to refer to the board.

    Read: 0