The same danger may be in question with some drugs used for weight loss.
The European Medicines Agency has informed about the possibility of increasing the risk of suicide about drugs containing liraglutide and semaglutide, which are used by Type-2 diabetes patients but are also used for weight loss. Evaluating the opening of an investigation, Psychiatrist Prof. Dr. Sermin Kesebir pointed out that such drugs may have suicidal thoughts and similar impulsive and agitating effects in some individuals. Pointing out that there may be the same risk of suicidality in some drugs used for weight loss, Kesebir also emphasized that physical exercise, regular and appropriate eating habits are essential to achieve and maintain an ideal weight, instead of weight loss drugs.
Drugs containing liraglutide and semaglutide have negative effects on psychological health.
An investigation was launched by the European Medicines Agency regarding the possibility of increasing the risk of suicide about drugs containing liraglutide and semaglutide, which are used by type-2 diabetes patients but are also used for weight loss. Referring to the properties of these active substances, Psychiatrist Prof. Dr. Sermin Kesebir, “These glucagon-like peptide 1 agonist drugs are effective on lipid (fat) metabolism as well as blood sugar regulation. Along with their effects on glucagon and insulin secretion from the pancreas, they are also associated with the hypothalamo-pituitary thyroid axis, adrenal and gonadal axis.
GLP-1 receptor agonists should not be over or under Kesebir explained the possible effects of this hormone on the brain and psychological health as follows:
“Basically, GLP1, which is assumed to be a neurotrophic factor (feeding nerve cells), has a bidirectional relationship with the systems I mentioned. Not more than enough as well as less than necessary is important. Just like the inappropriate use of antidepressants, some individuals may have suicidal thoughts and similar impulsive and agitating effects.”
The same danger may exist with some drugs used for weight loss
In general Pointing out that there may be the same risk of suicidality in drugs that are used to lose weight, some of which are smuggled, used without a prescription or sold over the internet, Kesebir said, “Mood disorder, be it depression or bipolar disorder, is also a disorder in the regulation of energy, in other words, psychomotor activity. Therefore, every disease and every treatment that is effective on metabolism and endocrine systems will also have effects on mood. Suicidal ideation is one of them.” He said. Underlining that physical exercise and nutrition habits should be regulated individually, Psychiatry Specialist Prof. Dr. At this point, Sermin Kesebir drew attention to the inappropriateness of referrals from the environment or non-physician. The treating physician should first be informed of the psychological symptoms that occur during treatments for physical illnesses (physical diseases), and a psychiatric consultation should be requested if necessary.”
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