*1-* What exactly is aquagenic urticaria? Why and what does it occur in humans? Could you elaborate a bit?
Aquagenic urticaria was first described in 1964.
It is a rare type of physical urticaria.
Intense itching, swelling and redness develop when the skin comes into contact with water.
Sometimes it may cause tingling, burning and stinging on the skin.
Rarely, headache, respiratory distress, headache. may cause dizziness and syncope.
Symptoms develop immediately or minutes after contact with water and disappear 30-60 minutes after contact with water is stopped.
There is no effect of water temperature, pH or psychogenic factors on the development of aquagenic urticaria.
Alcohol or other organic solvents are not effective in the development of aquagenic urticaria.
Although the exact cause is not known, some toxic substances or antigens secreted from the sebaceous glands in the skin after the skin comes in contact with water are the substances that cause itching on the skin (histamine). ) is thought to cause release.
*2-)* Is it a very common disease in the world? Are there data officially announced by WHO or other institutions? In addition to this question, is it also seen in our country? Have any cases been reported on this subject?
To date, 100 cases have been described in the literature.
It is more common in women than men, it usually starts in adolescence.
Although most of the cases are sporadic, familial cases have been reported.
Although association with some syndromes has been reported, it is thought to be coincidental. To date, the gene related to the disease has not yet been identified.
Cases from our country have been reported in the literature.
A case associated with thyroid cancer was reported by Özkaya E et al.
*3-)* How exactly is a person diagnosed with aquagenic urticaria? Are certain tests performed, what is the way to diagnose?
To confirm the diagnosis, water provocation test (water contact test) is applied.
The development of itchy rashes on the skin after the application of water with wet cloths on the upper part of the trunk, usually on the back, confirms the diagnosis.
Laboratory blood tests of patients with aquagenic urticaria are normal.
*4-)* Is only the skin affected?
Aquagenic urticaria on the skin, which starts after the contact of water, passes after the contact is stopped.
It usually does not show any systemic symptoms.
The patient's laboratory findings are normal.
Patients with aquagenic urticaria usually do not have any problems while drinking water, but difficulty in swallowing due to edema developing in the throat and Cases with respiratory distress have been reported.
Water has been reported to cause swelling in the uvula (uvula; uvula), causing difficulty in swallowing.
*5-)* Drinking water how do people with this disease meet their water needs? In the news, it is written that instead of water, drinks such as pomegranate juice have to be consumed. Don't these kinds of drinks have a negative effect?
Patients with aquagenic urticaria usually do not have any problems while drinking water, but cases with swallowing difficulties and respiratory distress due to edema in the throat have been reported.
< br /> *6-)* Raindrops and tears also cause reactions. What kind of skin conditions occur in such contacts in aquagenic urticaria? urticaria has been reported.
After the contact of water and secretions, itching, tingling and burning develop on the skin.
Complaints disappear 30-60 minutes after liquid contact is stopped.
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