It has been clinically shown that the duration of effect increases as Botox injections are performed at regular intervals.
Botulinum A toxin injections (botox) It is the most frequently performed cosmetic procedure in the USA. Its first use on humans was in 1980 by Dr. Alan Scott in the field of strabismus treatment and blepharospasm. The first studies on its use for wrinkle treatment were published by Carruthers et all in 1992. The first area they applied was between the eyebrows.
MECHANISM OF BOTOX EFFECT
The toxin is a 97 kDa (heavy chain) consisting of 1295 amino acids and 52 amino acids. It consists of two chains of kDa (light chain) connected by disulfide bonds.
The heavy chain binds to the membrane of nerve cells, allowing the light chain to pass into the cell fluid, and the light chain binds the protein called SNAP-25, which causes acetylcholine vesicles to enter the cell. prevents it from moving inside. As a result, neurotransmitter release into the synaptic gap does not occur and presynaptic neural block occurs.
Botox; It does not directly affect the injected skin. It prevents the contraction of the muscle that causes wrinkles on the skin and begins to show its effect.
Clinically, 2nd day after botox injection. It starts to take effect on days 2-4. It reaches its maximum effect within weeks and shows its effect. The beneficial effects of Botox last for an average of 3-6 months and this period varies from person to person. It takes much longer for all effects of Botox to disappear completely, but these effects are not visible effects, but effects shown in clinical trials.
The longer Botox injections are performed at regular intervals, the longer the effect lasts. It has been clinically shown that it increases.
Botox does not completely paralyze the muscles, but it causes a loss of strength, and this loss of strength is sufficient for the desired cosmetic result.
cosmetic result.
Situations where Botox can be used are summarized as follows:
1-facial wrinkle treatment ( face and upper lip )
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2-hand and armpit sweating treatment&nbs p;(duration of effect varies between 12-14 months when done properly)
3-migraine treatment (duration of effect varies between 10-14 months when done properly)
4-neck area wrinkle and tape treatment
5-anal fissure (there are studies showing that it has results similar to surgical treatment)
BOTOX TECHNICAL AND MEDICAL INFORMATION
The difference between an experienced botox injector and a technician (non-commercial persons, nurse, esthetician, etc.) ends in the concept of the functional anatomy of the face. Each patient's facial structure and anatomy is different, and the dose applied to each patient varies according to this anatomy and many other dynamics.
For this reason, when having botox, make sure that the practitioner is a plastic surgeon or dermatologist. .
The effects of Botox are completely temporary because the nerve cell block in its mechanism of action returns to normal over time. The effects of botox vary from person to person and last for an average of 3-6 months.
When you think about it, the need to have botox twice a year properly and the need to have it done 4-5 times a year without knowing how many doses are administered at very low prices. It is very worrying for us plastic surgeons that not only is there a loss of time and money, but also the destruction of botox's ability to treat facial wrinkles.
BUY BOTOX APPLICATION AND EYEBROW LIFT WITH BOTOX
There are two muscles in the forehead area called frontalis that help lift the eyebrows up. And botox injections into these muscles can be done to reduce wrinkles in the forehead area and lift the eyebrows up. Brow lift with Botox procedure can be performed safely up to 6 mm. Simply put, to raise the eyebrows, an injection is made into the muscles that lower the eyebrows. Applying too much botox to the middle part of the forehead causes MrSpock-looking eyebrow structure and also causes increased wrinkles on the eyebrow.
Eyebrow lift with Botox. brow lift to maximize By injecting the parts of the forehead muscle that are not responsible for the eyebrows (i.e. the outer areas of the eyebrows), the eyebrows are lifted by pulling the parts that lift the eyebrows higher. However, if we want the forehead wrinkles to be corrected at the same time, then the eyebrows will not lift to the desired extent because injections are made to the areas above the eyebrows to eliminate the forehead wrinkles. A careful examination is required to lift the outer parts of the eyebrows, and for this your doctor will ask you to laugh repeatedly and in the meantime decide whether the tips of the eyebrows can be lifted. There are no fixed points for lifting the eyebrows, and these points vary depending on the anatomy of each patient. For this reason, an effective examination before application is essential.
WHAT AREAS IS BOTOX APPLIED
Botoxcan be applied to almost every part of the face area. The places I apply it most often are the upper lip, forehead, crow's feet and middle of the eyebrow. The areas that I persistently avoid applying and do not apply even though my patients insist on it are the wrinkles in the lower eyelid area and the wrinkles on or near the upper eyelid.
There are many techniques when applying Botox to the forehead area. Each doctor may apply it differently. What I tell my patients about the forehead area, and what I like to see, is the expression 'you will be able to lift your eyebrows, but you will not have wrinkles'. This is one of the biggest signs of a natural botox and many people cannot understand that you have had botox.
It is necessary to be very careful when applying botox for crow's feet and it occurs in 1-2% of patients. Drooping of the upper eyelid may occur. The reason for this is that the muscle that lifts the upper eyelid up and the muscle that forms crow's feet are located very close together, and these muscles are anatomically thinner in some people. This effect may occur because Botox spreads from the point where it is applied to neighboring points. Drooping upper eyelid is completely temporary and disappears after days 4-6. It returns to normal within weeks and some medications used to reduce discomfort are relieved. Eye drops are also available. .
The other area where Botox is applied is the area between the eyebrows, and most of us have the biggest problem in this area. One of the reasons why the wrinkles between the eyebrows are stubborn is that there is more than one muscle that causes the wrinkles between the eyebrows.The wrinkles between the eyebrows are corrected with botox application. However, if there are wrinkles and depths present in normal posture, additional methods should be used (filling, fat injection, etc.). If the patient does not want additional methods, passive wrinkles between the eyebrows will gradually decrease with regular botox application every 3-4 months, and again, although the number of repetitions varies from person to person, the wrinkles between the eyebrows will be reduced gradually. They will still be in a much better position than before.
Since the wrinkles between the eyebrows are formed as a result of the contraction of many muscles, I think that this is the place where the most care and attention should be paid. An experienced specialist analyzes which muscles contract when the patient frowns and causes wrinkles, and applies the application to those areas, naturally resulting in much better results.
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