Low Grade Squamous Cells

LSIL; It refers to low-grade squamous cells.

The diagnosis of LSIL is reported in 2.9% of all PAP smear tests.

High-risk HPV DNA positivity is present in 77% of LSIL cases. has been detected.

When LSIL is detected, CIN 2-3 (HSIL) is detected at a rate of 12-16% in the first colposcopy performed at the beginning.

ASC. -CIN 2-3 is detected at the same rate in high-risk HPV DNA positive cases with US and LSIL detected and they are followed-up and treated in the same way.

• Colposcopy and COLPOSCOPY for cases with LSIL detected. Accompanied biopsy is recommended.

• In LSIL cases where CIN 2-3 cannot be detected in adequate colposcopic examination, HPV DNA test at the 12th month or PAP smear cytology follow-up twice with an interval of 6 months is recommended. If HPV DNA negative is detected during these follow-ups or if two consecutive PAP smears are reported negative, the patient is included in the routine screening program.

• If HPV DNA positive and/or ASC-US and above lesions are reported during the follow-up. Colposcopy is recommended.

• If the diagnosis of CIN is not reported in LSIL cases, diagnostic excisional surgical methods (LEEP-CONIZATION - HYSTERECTOMY) are not recommended.

• ECC- Endo-cervical curettage is recommended for cases where colposcopy is inadequate or no lesion can be detected during colposcopy. Endo-cervical curettage is not recommended for pregnant women diagnosed with LSIL.

• HPV DNA test is not recommended in cases diagnosed with adolescent LSIL under the age of 20. Even if HPV DNA positivity is present in these patients, the follow-up is not changed.

• Colposcopy is recommended if there is HSIL in the 12-month cytology follow-up under the age of 20 and ASC-US or above lesion in the 24-month cytology follow-up.

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LSIL FOLLOW-UP IN POSTMENOPAUSAL CASES

• HPV DNA test is recommended.

• If HPV DNA test is negative or CIN is not detected in colposcopy, PAP smear and cervical cytology are recommended at 12 months.

• HPV DNA positive or ASC-US and above lesion in cytology If available, Colposcopy is recommended.

• Sequential PAP smear follow-up (twice in the 6th and 12th months)

• Two consecutive PAP smears If the test is negative, it is taken into a routine follow-up program.

• Colposcopy is recommended.

 

LSIL IN PREGNANT CASES FOLLOW-UP

• Cytological follow-up is recommended twice with an interval of 6 months for pregnant patients under 20 years of age.

• Over 20 years of age. Colposcopy should be preferred in pregnant patients.

• If CIN 2-3 is not suspected in the initial colposcopy, postpartum follow-up is recommended.

• ECC-Endo-cervical curettage is not recommended in pregnant women.

 

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