The number of eggs decreases in a programmed manner throughout a woman's life, even while she is in the womb, and fertility decreases to a minimum approximately 10 years before the expected age of menopause.
The number of eggs is as expected depending on advanced age; or may decrease at younger ages. The history should be questioned very carefully as many factors such as previous ovarian operations, chocolate cyst, radiotherapy or chemotherapy, smoking, genetic disorders, a close relative in the family who went through early menopause, or autoimmune diseases can cause this.
The most practical and first to be checked among the tests. is the central follicle count. On ultrasound on the 3rd day of menstruation, 6-7 follicles in each ovary indicate good ovarian reserve, 12 or more polycystic ovaries, and fewer than 5 central follicles indicate low ovarian reserve. Observing 1-2 antral follicles indicates a very low chance of pregnancy.
If FSH exceeds 10 on the 3rd day of menstruation, it also indicates low ovarian reserve. It is very important that it is examined at the right time.
If the E2 value is too low or high when examined on the 3rd day, it reduces the chance of pregnancy.
If the AMH value is below 1.5, it means miscarriage reserve; if it is above 2.5, It mostly indicates polycystic ovary.
WHO IS EGG FREEZING (OOCYTE CRYO) SUITABLE FOR?
This procedure is applied to single women whose ovarian reserve has decreased when they are under 35 years of age or who are over 35 and have no pregnancy plans in the near future. are candidates for. It should be explained from the beginning that very few eggs can be retrieved in women with severely reduced egg reserves, and that only enough eggs can be obtained by repeating the procedure several times.
HOW IS THE EGG FREEZING PROCESS DONE?
For egg freezing. The treatment is actually the same as in vitro fertilization treatment until the last stage. Hormones given to grow more than one follicle in the ovaries are usually given by subcutaneous injections, and sometimes by drugs called clomiphene citrate or letrozole, either alone or as a supplement. On the 5th day of the treatment, which will last an average of 10-12 days, an injection called an antagonist is added to prevent the eggs from hatching early, and when the follicles grow sufficiently, the pregnancy hormone called hCG is administered and the effect of the LH hormone is reduced. It is harvested under anesthesia at the 36th hour after being allowed to mature. If the collected eggs are mature, they are frozen without fertilization with sperm, unlike in vitro fertilization.
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