The pancreas is a very important organ related to food and energy metabolism, producing the enzymes necessary for the digestive system and the hormones necessary for the regulation of blood sugar. Pancreatic cancer is a dangerous type of cancer because it causes problems in many important mechanisms in the body and has an aggressive course. During the stages of pancreatic cancer, there are usually no symptoms in the 1st and 2nd stages, but since the symptoms are noticed in the 3rd and 4th stages, it is life-threatening. Symptoms of pancreatic cancer may include loss of appetite, weight loss, weakness, nausea, vomiting, bloating, diarrhea, and the unexpected onset of diabetes. There are many genetic or environmental risk factors in the development of pancreatic cancer.
Non-genetic and sudden onset diabetes can be a sign of what?
In the vast majority of patients (approximately ¾%) diagnosed with pancreatic cancer impaired glucose metabolism or type 2 diabetes. There is a bidirectional relationship between type 2 diabetes and pancreatic cancer. In other words, pancreatic cancer can be seen at a rate of ¼ in patients diagnosed with type 2 diabetes. For this reason, diabetes is among the top risk factors for pancreatic cancer. In type 2 diabetes, insulin is produced from the beta cells of the pancreas, but blood sugar cannot be lowered because insulin resistance is seen in the tissues. In this case, although the pancreas tries to produce more insulin to lower blood sugar, it is not helpful. The effort of the pancreas to produce insulin and its exposure to high levels of insulin are seen as the main cause of pancreatic cancer. For this reason, it is recommended that people diagnosed with type 2 diabetes and especially older people suspect pancreatic tumor and have pancreatic imaging done.
Do problems in fat metabolism affect the development of pancreatic cancer?
One of the most important risk factors for pancreatic cancer obesity and high body fat percentage. Each 5-value increase in the body mass index calculated according to the weight-to-height ratio increases the risk of pancreatic cancer by 10%. For this reason, one of the risks that people with overweight and high cholesterol (Hypercholesterolemia) should consider is pancreatic cancer.
Is pancreatic cancer a common cancer? Why is it important
Although pancreatic cancer is not among the most common cancers, the reason why it is a well-known cancer is that it has an aggressive course and is life-threatening because it is detected in the late stages. It is thought that pancreatic cancer, which has a high risk of death, will take the second place among cancer-related deaths in the coming years. Pancreatic cancer is difficult to diagnose because it usually does not cause symptoms in the early stages. The earlier it is diagnosed, the higher the success rate of pancreatic cancer treatment.
What are the factors that increase the risk of pancreatic cancer?
One of the most important factors that increase the risk of pancreatic cancer is smoking, pipe smoking and smoking. using tobacco products such as cigars or being in the environment. Tobacco use increases the risk of pancreatic cancer by up to 70%. Other factors that significantly increase the risk of pancreatic cancer include high cholesterol, obesity, excessive alcohol use, diabetes, chronic pancreatitis and some infections.
Which gene is associated with pancreatic cancer? What is the share of genetic predisposition in pancreatic cancer?
It has been determined that only 5% of pancreatic cancer cases have genetic origin. However, if 3 or more people from family and blood relatives have pancreatic cancer, the risk of developing pancreatic cancer increases 57 times. Although only a single pancreatic cancer gene could not be identified as a result of genetic studies, it was determined that BRCA 1, BRCA2 and 6174delT mutations were effective on pancreatic cancer. Pancreatic cancer is common in African, American, and Ashkenazi Jews. It is also known that genetically transmitted diseases such as hereditary pancreatitis, hereditary nonpolyposis colorectal cancer, hereditary breast-ovarian cancer, familial multiple mole melanoma syndrome, Ataxia-telangiectasia, Fanconi anemia, Peutz-Jeghers syndrome and cystic fibrosis increase the risk of pancreatic cancer.
What are the foods that increase the risk of pancreatic cancer? Processed meat products such as sausage, salami, sausage and red meat are also foods that increase the risk. special As with any cancer, pancreatic cancer also increases the risk when it is grilled and burnt. In general, there is no clear data on the risk of pancreatic cancer with foods with high sugar content, which increase the risk of cancer and are thought to cause the progression of cancer because it feeds cancer cells. Another product for which there is no clear data about a definite increase in cancer risk is soda. Although there is a link between soda and pancreatic cancer, it is not known whether it is because it increases cancer or because it is used to relieve stomach ailments, which are symptoms of cancer. For this reason, simple complaints such as stomach problems should not be overlooked and a doctor's examination is recommended. Coffee consumption recommended to prevent pancreatic cancer
Coffee consumption with or without caffeine reduces the occurrence of pancreatic cancer by about half. Since coffee consumption protects heart health and the risk of pancreatic cancer, it is recommended to consume 1 cup of Turkish coffee a day. Pancreatic cancer can be protected by measures to be taken since it causes factors. Also, do not use it.
- Have an ideal weight for your height, you are overweight If you can, try to give it.
- Burn calories by exercising regularly and reduce the amount of calories you take in daily.
- Consume fresh vegetables and fruits every day by paying attention to a healthy diet.
- Simple reduce sugar and saturated fat consumption.
- Avoid processed meat products and focus on white meat by reducing red meat.
- Check exposure to chemicals in all areas minimize it and follow the safety precautions.
- Former smokers
- Diabetes patients
- Those with pancreatic or biliary tract pathology
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