In vitro fertilization treatment may be necessary as a result of examinations and tests for couples who cannot achieve pregnancy naturally despite having regular and unprotected intercourse for a year. 10-15% of couples of reproductive age have infertility problems, and approximately one in every 6 women receive professional help for infertility.
If the uterine canals are blocked and sperm count and quality are severely impaired, pregnancy can be achieved with other treatment methods. If infertility cannot be achieved, if there is unexplained infertility, if there are adhesions in the abdomen due to endometriosis, previous abdominal surgeries or gynecological infections, or if a diagnosis needs to be made at the embryo stage due to a hereditary disease, in vitro fertilization treatment may be necessary, it is useful to get consultancy from your doctor on this subject.
How Many Times Can IVF Treatment Be Tried?
In order to achieve a happy ending in IVF treatment, it is necessary to believe in the treatment without despairing. Even if pregnancy cannot be achieved, one should not give up immediately. In vitro fertilization treatment is not a treatment that can be applied once. Pregnancies are common after new attempts at in vitro fertilization treatment, which had unsuccessful results in the first application.
There is no set number for how many times the treatment will be tried. In line with the wishes of the spouses and with the recommendation of the physician, new trials can be made if the spouses' health conditions are appropriate.
Couples who have not been able to achieve pregnancy despite trying natural methods or who have not been successful with other reproductive techniques should not expect a miracle from in vitro fertilization treatment. If necessary, after the first unsuccessful attempt, the reasons for this should be determined.
If couples have intense expectations that they will have a baby with in vitro fertilization treatment, the number of attempts can be increased, and it is not harmful for the spouses to make new attempts without wearing themselves out. In vitro fertilization treatment can be repeated when both partners are suitable, leaving a certain period of time between each new treatment. If the failures experienced after the trials affect the spouses negatively, it may be necessary to take a break or even end the practice.
After unsuccessful attempts at in vitro fertilization treatment, the chances may gradually decrease in repeated treatments. The right thing to do here is to try unsuccessfully before attempting new attempts. The reasons for the experiment should be investigated. After the causes are identified and corrected, in vitro fertilization treatment should be applied. Constantly embarking on new experiments without doing any research will cause spouses to become worn out. Unless the cause of failure is determined, it would be appropriate not to make a new attempt.
- Abnormalities that may prevent the embryo from adhering, such as intrauterine adhesions in women, myomas or polyps in the uterus, should be corrected by hysteroscopy method.
- Anomalies that prevent the embryos from adhering.
- Another reason is the accumulation of fluid in the woman's tubes due to blockage. This condition, called hydrosalpinx, is diagnosed by ultrasonography or uterine film, and by closing the part of the tubes close to the uterus by laparoscopy or by surgically removing the tubes, this fluid is prevented from flowing into the uterine cavity and preventing the embryos from attaching.
- Thyroid gland diseases occur in the brain. Hormonal disorders, such as the increase in the milk hormone (prolactin) secreted from the pituitary, also prevent embryo development and attachment in the uterus. These need to be investigated and treated with medications.
- Polycystic ovary disease and the increase in insulin hormone it causes make it difficult to get pregnant and can also lead to miscarriages. For this purpose, the chance of pregnancy can be increased by giving diabetes medications that reduce insulin resistance.
- Whether there are congenital or acquired problems with the immune and coagulation system should be investigated by performing advanced blood tests and, when necessary, they should be treated with the use of appropriate medications.
- Detailed sperm analysis should be performed in men. If there is a significant decrease in sperm count, lack of motility or deformity in sperm, genetic tests (such as chromosome analysis, Y chromosome microdeletion test, sperm FISH test) should be performed. If a problem is detected in these tests, it is necessary to use sperm cell selection and Preimplantation Genetic Diagnosis (PGT) (genetic examination and diagnosis before transfer to embryos) techniques in a new in vitro fertilization treatment.
- Many methods have been developed to increase the success of in vitro fertilization treatment. Methods that increase the success rate other than preimplantation genetic diagnosis:
- Hysteroscopy and hysteroscopic endometrial damage
- Removal of Tubes Before IVF
- Micro TESE
- Embryoscope
- Assisted Hatching (AHA)
- Endometrial co-culture (Intrauterine tissue culture)
- Blastocyst transfer
- Embryo freezing
- Preimplantation Genetic Diagnosis (PGT)
- Pregnancy vaccine
- Natural cycle and mini IVF
In conclusion Although pregnancy is often achieved in the first month of in vitro fertilization treatments, repeated attempts may sometimes be required. The important thing is to identify all the problems that may prevent success before starting the treatment and to hold your baby with the least financial and moral fatigue.
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