In what cases is in vitro fertilization performed? Is it applied only for female infertility? Does the woman's age matter in the in vitro fertilization method?
In vitro fertilization treatment is a method applied if pregnancy cannot be achieved by natural means. Although they are not recommended as the first step, they can be recommended as the first step after determining the woman's age, marriage duration, ovarian reserve, sperm status and whether the tubes are open. Approximately one third of couples who consult a doctor with infertility have a female-related problem. Again, approximately 1 in 3 cases of infertility are caused by men. In the remaining 1 in 3 cases, we cannot reveal any reason.
When asked what is the most important factor affecting the success of in vitro fertilization treatment, it would not be wrong to say 'woman's age'. Of course, many factors are effective in success, but age is the most important among them.
What is the microinjection method? In what cases is it done?
What is done in this method, also called ICSI, or intracytoplasmic sperm injection; It is the introduction of a selected and prepared sperm cell into the obtained egg with the help of a special needle. It is especially used in the presence of very low or no sperm count, but sperm taken with the help of biopsy from the testicular tissue called TESE. However, today, it has become a part of standard in vitro fertilization treatment.
How is embryo transfer done? Is it a painful procedure?
The transfer process is the process of introducing the prepared and selected best quality embryo or more than one embryo into the uterus with the help of a special catheter and ultrasound guidance. Pain is not expected during or after this procedure.
How is embryo freezing performed and how can embryos be stored?
The process of freezing embryos, sperm or eggs is called vitrification. It is based on the principle of rapid freezing of tissues suddenly exposed to very low temperatures. With this process, damage to frozen tissues is minimal and survival rates increase after thawing. With this technology, a new era has opened in in vitro fertilization treatment.
With fresh embryo transfer or frozen embryo transfer? More chances of pregnancy?
Frozen embryo transfer is very useful in some situations that prevent fresh transfer, especially during treatment. For example, if there is an intrauterine or hormonal problem before fresh embryo transfer, embryos can be frozen without transfer. In this case, frozen embryo transfer is very advantageous. Again, when the number of eggs collected during treatment exceeds a certain threshold, the chance of pregnancy decreases with fresh transfer. In such cases, frozen embryo transfer is preferred. However, it is always too early to make frozen transfers for everyone.
What is the Microchip technique in in vitro fertilization treatment?
In the chip technique, which is a fairly new technology, sperms are transferred. They are left in special environments to allow them to swim, and the selected sperm obtained from there are used for the process. The main principle here is based on the assumption that sperm that can pass through these environments will be more durable and healthy. However, today it is too early to use it routinely.
How to apply an embryo monitoring system that ensures the selection of the right embryo?
This system allows embryos to be processed. It is the process of observing the devices called incubators in which they are left to grow with the help of a camera. The most prominent and best developing embryos that are constantly monitored are the embryos that are candidates for transfer.
What is embryo adhesive? Does the chance of getting pregnant increase with embryo adhesive?
Nowadays, there are many innovations, especially in the molecular field. In particular, the diversity of techniques that help embryos adhere is increasing day by day. What is done in this process is that the embryos are exposed to some special substances before the transfer and these fluids are introduced into the uterus along with the embryo during the transfer. Thus, it is expected to increase the chance of retention. It is especially recommended in cases of advanced age and poor embryo quality.
What is the contribution of IMSI Technology to in vitro fertilization treatment?
What is done in IMSI technique is special tools. With the help of sperms, sperms can be magnified approximately 6000 times and their shapes can be seen. e is their scoring. Thus, the sperm with the highest score in terms of shape is selected as the candidate sperm to be transferred into the egg.
Are stem cells used in in vitro fertilization treatment?
Stem cells obtained from tissues can be transformed into egg or sperm cells with some special growth factors and hormones. However, these technologies are still in the animal testing phase. Significant results are expected to be obtained in humans within the next 20 years.
What is the mini IVF method in in vitro fertilization treatment?
Especially drug-free in vitro fertilization. In the 'mini in vitro fertilization' method, also called baby, eggs are grown with pills without the use of hormones, which are normally given as injections in certain doses every day, and very little needle use is on the agenda. In this way, the injection is avoided. However, it should not be forgotten that there is a slight decrease in the number of eggs obtained. It is useful to use it in selected cases.
What is crinobiology in in vitro fertilization treatment? In what situations is it used? Is there any risk?
Cryobiology is the technique of freezing tissues. Nowadays, special methods called vitrification are used. Thus, embryos, sperm, eggs or ovarian and testicular tissues can be frozen. Tissue or cells may be frozen for reproductive preservation, especially before cancer treatment. Tissue-cell freezing is recommended, especially before treatments that may be harmful to the ovaries or testicles. In individuals who have completed cancer treatment, long-term dissolution of sperm-eggs or tissues and healthy births have been achieved after in vitro fertilization treatment.
Can the stress hormone in the hair predict the chance of success in in vitro fertilization?
In today's evidence-based medical logic, there is not yet enough data on this subject.
What are the reasons for recurrent in vitro fertilization failures?
If success is not achieved in more than one attempt, both the woman, the man and the resulting embryo need to be re-evaluated and criticized. Sperm analysis should be done again and sperm DNA damage should be checked. Inner uterus in women It should be evaluated and if there is a problem, it should be resolved. Genetic analyzes for men and women should be performed, and even genetic screening of embryos should be brought to the agenda. If unsuccessful attempts were made with high-quality embryos, attachment problems should be investigated, and if the embryos are of poor quality, examinations regarding this issue should be performed. Of course, possible problems during the transfer phase should also be eliminated.
Does in vitro fertilization treatment consume ovarian reserves?
With in vitro fertilization treatments No decrease in reserves is expected. Because, with each treatment, the follicle carrying approximately 10-15 mature eggs grows. However, at that time, we know that there are many more egg cells as reserves.
Can in vitro fertilization carry the risk of being born with weak sperm? Will this cause problems in the future?
Until now, the problem of infertility in children born and raised through in vitro fertilization has not been revealed. Unless there is a genetically inherited problem, infertility problems are not observed in in vitro fertilization children.
Can genetic diseases be seen in the embryos of couples with normal chromosome analysis?
This possibility always exists. Genetic diseases can be observed due to problems in the division stages of embryos, as well as spontaneous mutations. However, these rates are quite low.
What can be done to improve sperm quality in in vitro fertilization treatment?
As general precautions; Quitting smoking, reducing alcohol and caffeine, losing weight, exercising, and careful nutrition (rich in vitamin D and omega-3) are general recommendations. Antioxidant treatment is beneficial, especially in cases with mobility problems or a high rate of DNA damage.
What awaits us in the future in in vitro fertilization treatment?
There are some important developments in the field of genetics. More genetic diseases can be diagnosed before embryo transfer with less cost and fewer errors. Pills, especially instead of injections, may become available in the near future to enlarge eggs. In summary, by prioritizing patient comfort, higher pregnancies can be achieved with less cost.
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