Side Effects of Vaccines

Local reactions

It is the most common side effect. It passes in 1-3 days and is harmless. Pain, redness, swelling and increased temperature are observed in the area where the vaccine is applied.

Systemic side effects

Fever, weakness, myalgia. are more general effects such as headache and loss of appetite. They are non-specific symptoms of any disease, and they may develop due to vaccination or other reasons. Vaccine-related fever or rash mostly occurs following live attenuated vaccines. Live vaccines must replicate themselves to generate an immune response. This happens because the natural state of the disease occurs in a mild form 3-21 days after vaccination. The viruses in these vaccines copy themselves in the mucus membranes of the ear and throat, but do not replicate in the lungs. For this reason, the resulting effects appear as a mild upper respiratory tract infection.

Allergic reactions

Vaccine antigen or cell It may occur due to another component of the vaccine, such as culture material, preservative, stabilizer, or antibiotic used to inhibit bacterial growth. Serious effects such as anaphylaxis can be life-threatening.

Anaphylaxis after vaccination

Anaphylaxis is a complication that develops once in a million after vaccination. It can be severe enough to be life-threatening. Therefore, anaphylaxis must be recognized and intervened immediately. Anaphylaxis is a hypersensitivity reaction that develops within minutes. It mostly occurs with skin and mucosal symptoms. Skin redness, urticaria, itching, swelling of the tongue and lips are observed. Symptoms related to the respiratory system are wheezing, noisy breathing, stridor, dyspnea, bronchospasm. Symptoms related to hypotension are syncope, hypotonia, collapse and incontinence. Gastrointestinal symptoms are crampy abdominal pain and vomiting. These symptoms may be confused with vasovagalsyncope. Some sensitive people may experience fainting (vasovagalsyncope) due to pain and fear during the injection. This condition is due to hypersensitivity of the autonomic cardiovascular system and is accompanied by sudden hypotension, bradycardia and loss of consciousness. he orders. It is harmless and consciousness returns in a short time.

Due to the risk of anaphylaxis, vaccinated people should be kept in the health institution for 20 minutes as a precaution.

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